1
general::
Intrinsically, considered alone. For example, In and of itself the plan might work, but I doubt that it will be approved. It is Also put simply as in itself, as in This account may be true in itself. [First half of 1600s]
American Heritage Idioms
2
general::
Phrase(s): in and of itself
considering it alone. • The idea in and of itself is not bad, but the side issues introduce many difficulties. • Her action, in and of itself, caused us no problem.
McGrawhill's American Idioms And Phrasal Verbs